top of page
  • Writer: Dr. Taha Murtaza
    Dr. Taha Murtaza
  • May 8
  • 4 min read

Written by Dr. Taha Murtaza


Netflix has released many movies, but some have an everlasting impact on the audience. One can enjoy a movie with a chips packet in one hand and a cold drink in another and experience magical vibes with his family and friends. Some movies on Netflix are extraordinary, the viewer can feel that he is in that movie somewhere. So, now get ready tight your seat belts, and move towards the journey of the best netflix movies of all time 2025.


10. The Super Mario Bros Movie

iknoweverything image showing mariobros poster

The Super Mario Bros Movie is an American movie released on 5th April 2023, produced by three mega industries, Universal Pictures, Illumination, and Nintendo. This movie is taken from a Nintendo video game that we all have enjoyed on Gameboy or any other device in our childhood. This movie is directed by Aaron Horvath and Michael Jelenic. This movie has a budget of 100 million US dollars. The voice cast includes Chris Pratt as Mario, Anya Taylor-Joy as Princess Peach, Charlie Day as Luigi, and Jack Black as Bowser.


This is an adventurous, comedy, and family-oriented picture.

iknoweverything image showing mario bos movie characters

The adventurous story focuses on brothers Mario and Luigi who are plumbers by occupation. They are separated and transferred to a mysterious land. In this story, there is a battle between Princess Peach's Mushroom Kingdom and Bowser's Koopas Kingdom.




9. Hillbilly Elegy


A drama and comedy movie directed by Ron Howard is a 2020 American movie based on Vance's book 2017, produced by Imagine Entertainment, and distributed by Netflix.


iknoweverything image showing hillbill elegy movie poster

This film is based on the true story of JD Vance who describes how he faced difficulties and uplifted his family when his family came to Ohio after World War 2.


Vance also describes the Appalachian culture. This culture promotes love and loyalty to the country despite violence. His mother has been portrayed as a drug addict but his grandmother makes his mother strong and responsible.



  1. We can be heroes


In 2021, here comes a most watched film with a powerful entry, directed, produced, and written by the same person named 'Robert Rodriguez'.


iknoweverything image showing heroes movie poster

The movie showcases a girl named 'Moreno' living with her dad Marcus. They meet different heroic children and go on an adventure to save the world.


The kids are inherited with different and unique superpowers. The viewer can enjoy how these kids use their superpowers and what they can do to save the world.



  1. Damsel


A film written by the writer of the blockbuster movie Fast X Dan Mazeau, directed by a director known for the film '28 weeks later, named 'Juan Carlos Fresnadillo'.


iknoweverything image showing damel movie poster

A hardworking decent girl married a prince which was recruited just to sacrifice her life for an ancient dept.


The girl faces many challenges and fights bravely.



  1. The gray man:


Gray Man is an action thriller movie based on a novel released in 2009. This novel has a continual of 10 more books.

iknoweverything image showing the gray man movie poster

This movie is made by the Ruso brothers who directed mega movies of Marvel i.e. Avengers, End Game, etc.


This movie is the most expensive movie on Netflix.


The movie focuses on an agent of the CIA named Six.


In this movie, the boxing skills of the actors are displayed nicely and the videography is very unique.



  1. Sniper The Rouge Mission:


    iknoweverything image showing sniper rogue mission movie poster

This movie is the 9th of the sniper series directed by Oliver Thompson.


The main cast includes Chad Michael as Brandon Beckett, Ryan Robbins as Zero, Brendon Sexton 3 as Gildie, and Siaka Atimoto as Lady Death.


This movie revolves around an agent named Brandon Beckett who started action against a ring that works on human sex trafficking. This is an action movie with outstanding cinematography.



  1. Woody Woodpecker:

iknoweverything image showing woodywood pecker movie poster

This movie is a family/comedy movie that features the cartoon character Woody.


The film stars Timothy Omundson, Graham Verchere, Jordana Largy, and Thaila Ayala, and features Eric Bauza as the voice of Woody Woodpecker.


This movie has been directed by Alex Zamm.


The story goes around a bird called Woody who protects his forest from a real estate lawyer who is going to build a house there.





  1. The life list:


    iknoweverything image showing the life list movie psoter

This movie has been released on 28th March, 2025. It is taken from the novel "The Life List" by Lori Nelson Spielman.

It covers both romance and comedy, directed by Adam Brooks


The main cast includes Sofia Carson, Kyle Allen, and Connie Britton.


This movie focuses on a teenage girl who struggles to learn some new life experiences fulfill new goals and face many difficult challenges to earn her bread after her mother's death from cancer.



  1. Life or something like it:

iknoweverything image showing life or something like it movie poster

The plot focuses on television reporter Lanie Kerrigan and her quest to find meaning in her life. The film was released on April 26, 2002.


Life or Something Like It is a 2002 American romantic comedy-drama film directed by Stephen Herek. It features Angelina Jolie and was largely filmed in the Seattle area.


The reporter Lanie interviews a person who calls himself a prophet and has the power to predict the future.


There is a big shocking twist in the life of the reporter after meeting with the so-called prophet.


Watch this movie to explore the hidden part.




  1. Havoc

    iknoweverything image showing havoc movie psoter

Havoc is a 2025 action thriller film written and directed by Gareth Evans. The film features a star-studded cast including:


The film is a co-production between the United States and the United Kingdom and was released by Netflix on April 25, 2025.


Following a botched drug deal, a battered detective must battle through the criminal underworld to save a politician's estranged son, uncovering a complex network of corruption and conspiracy that entangles his whole city.




 
 
 
  • Dr. Rukhsar Zehra
  • May 5
  • 5 min read

فارمیگیٹ کیپسول کا استعمال


Written by Dr. Rukhsar Zehra [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.

murtazacommunitypharmacy image showing formiget 200+6 mcg capsule box

Brand name:

Formiget


Generic name:

Budesonide + formoterol Fumerate Dihydrate


Available dosage forms and their doses

Dry Powder inhaler capsule


Available for administration as:

  • Dry Powder Inhaler Capsules 200mcg + 6mcg

    Each capsule contains: Budesonide BP… 200mcg Formoterol fumarate dihydrate Ph.Eur… 6mcg


  • Dry Powder Inhaler Capsules 400mcg + 12mcg

    Each capsule contains: Budesonide BP… 400mcg Formoterol fumarate dihydrate Ph.Eur… 12mcg


Price:

Rs.14/Cap or Rs. 140/strip


Therapeutic class:

Bronchodilator and Anti-Asthmatic.


Pharmacological class:

Budesonide is Corticosteroid and Formoterol fumarate dihydrate is a long-acting selective

β2 adrenoceptor agonist (LABA)


Manufacturer:

Getz Pharma


Storage

  • Do not store above 30°C.

  • Protect from sunlight and moisture.


Prescription drug:

Yes, it requires a prescription.


Clinical Pharmacology (mechanism of action):

Budesonide and Formoterol fumarate dihydrate have different modes of action and show additive effects in terms of reduction of asthma exacerbations and COPD exacerbations.


The specific properties of budesonide and formoterol allow the combination to be used

either as maintenance and reliever therapy or as maintenance treatment of asthma and for symptomatic treatment of patients with moderate to severe COPD.


Budesonide is a glucocorticosteroid which when inhaled has a dose-dependent anti -inflammatory action in the airways, resulting in reduced symptoms and fewer asthma

exacerbations.


Budesonide has also been shown to decrease airway reactivity to both direct and indirect challenges in hyperreactive patients.


Formoterol fumarate dihydrate is a selective β2 adrenoceptor agonist that when inhaled

results in rapid and long-acting relaxation of bronchial smooth muscle in patients with

reversible airway obstruction.


Indications and dosages:

Asthma:

Formiget (Budesonide + Formoterol fumarate dihydrate) is indicated in adults and adolescents (12 years and older) for the regular treatment of asthma, where the use of a

combination (inhaled corticosteroid and long-acting β2 adrenoceptor agonist) is appropriate


Chronic Obstructive Pulmonary Disease (COPD):

Formiget (Budesonide + Formoterol fumarate dihydrate) is indicated in adults, aged 18

years and older, for the symptomatic treatment of patients with COPD with forced expiratory volume in 1 second (FEV1)



murtazacommunitypharmacy image showing formiget 400+12mcg capsule box


Dosage & Administration:

Formiget is not intended for the initial management of asthma. The dosage of the

components of Formiget are individual and should be adjusted to the severity of the disease.


This should be considered when treatment with combination products is initiated and when the maintenance dose is adjusted.


Patients should be regularly reassessed so that the dosage of Formiget (Budesonide +

Formoterol fumarate dihydrate) remains optimal.


The dose should be titrated to the lowest dose at which effective control of symptoms is maintained.


When long-term control of symptoms is maintained with the lowest recommended dosage, then the next step could include a test of inhaled corticosteroid alone.


In usual practice when control of symptoms is achieved with the twice-daily regimen, titration to the lowest effective dose could include Formiget given once daily.


Increasing use of a separate rapid-acting bronchodilator indicates a worsening of the underlying condition and warrants a reassessment of asthma therapy.


  • Adults (18 years and older): The recommended dose for adults is 1-2 inhalations twice daily.

  • Some patients may require up to a maximum of 4 inhalations twice daily.

  • Adolescents (12 – 17 years): The recommended dose for adolescents is 1-2 inhalations twice daily.


Administration:

The capsule is taken through a device known as prohaler. (getz pharma)


Side Effects:

  • Common: Candida infections in the oropharynx, pneumonia (in COPD patients), headache, tremor, palpitations, mild irritation in the throat, coughing and hoarseness.


  • Uncommon: Aggression, psychomotor hyperactivity, anxiety, sleep disorders, dizziness, blurred vision, tachycardia, nausea, bruises and muscle cramps.


  • Rare: Immediate and delayed hypersensitivity reactions, e.g. exanthema, urticaria, pruritus, dermatitis, angioedema and anaphylactic reaction, hypokalaemia, cardiac arrhythmias, e.g. atrial fibrillation, supraventricular tachycardia, extrasystoles and bronchospasm.


  • Very rare: Cushing’s syndrome, adrenal suppression, growth retardation, decrease in bone mineral density, hyperglycaemia, depression, behavioural changes, taste disturbances, cataracts and glaucoma, angina pectoris. prolongation of QTc-interval and variations in blood pressure.


Interactions:

  • Potent inhibitors of CYP3A4 (e.g. ketoconazole, itraconazole, voriconazole, posaconazole)

  • clarithromycin

  • telithromycin

  • nefazodone

  • HIV protease inhibitors are likely to increase plasma levels of budesonide and concomitant use should be avoided.

  • β-adrenergic blockers can weaken or inhibit the effect of formoterol. Budesonide +Formoterol fumarate dihydrate should therefore not be given together with β-adrenergic blockers (including eye drops) unless there are compelling reasons.

  • Concomitant treatment with quinidine, disopyramide, procainamide, phenothiazines, antihistamines (terfenadine) and tricyclic antidepressants can prolong the QTc-interval and increase the risk of ventricular arrhythmias.

  • L-dopa, L-thyroxine, oxytocin and alcohol can impair cardiac tolerance towards β2 sympathomimetics.

  • Concomitant treatment with monoamine oxidase inhibitors, including agents with similar properties such as furazolidone and procarbazine, may precipitate hypertensive reactions.

  • There is an elevated risk of arrhythmias in patients receiving concomitant anaesthesia with halogenated hydrocarbons.

  • Concomitant use of other β-adrenergic drugs or anticholinergic drugs can have a potentially additive bronchodilating effect.

  • Hypokalaemia may increase the disposition towards arrhythmias in patients who are treated with digitalis glycosides.

  • Hypokalaemia may result from β2-agonist therapy and may be potentiated by concomitant treatment with xanthine derivatives, corticosteroids and diuretics.


Pregnancy:

Only after special consideration should Budesonide + Formoterol fumarate dihydrate be used during the first 3 months and shortly before delivery. Because β-agonists, including formoterol may potentially interfere with uterine contractility, due to a relaxant effect on uterine smooth muscle, Budesonide + Formoterol fumarate dihydrate should be used during labour only if the potential benefit justifies the potential risk.


Lactation:

Budesonide is excreted in breast milk. Administration of Budesonide + Formoterol fumarate dihydrate to women who are breast-feeding should only be considered if the expected benefit to the mother is greater than any possible risk to the child


Precautions:

  • It is recommended that the dose is tapered when the treatment is discontinued and should not be stopped abruptly.


  • Serious asthma-related adverse events and exacerbations may occur during treatment with Budesonide + Formoterol fumarate dihydrate. Patients should be asked to continue treatment but to seek medical advice if asthma symptoms remain uncontrolled or worsen after initiation with Budesonide + Formoterol fumarate dihydrate.


  • If the patient experiences paradoxical bronchospasm Budesonide + Formoterol fumarate dihydrate should be discontinued immediately, the patient should be assessed and an alternative therapy instituted, if necessary.


  • Potential effects on bone density should be considered particularly in patients on high doses for prolonged periods that have co-existing risk factors for osteoporosis.


  • If there is any reason to suppose that adrenal function is impaired from previous systemic steroid therapy, care should be taken when transferring patients to Budesonide + Formoterol fumarate dihydrate therapy.


  • Budesonide + Formoterol fumarate dihydrate should be administered with caution in patients with thyrotoxicosis, phaeochromocytoma, diabetes mellitus, untreated hypokalaemia, hypertrophic obstructive cardiomyopathy, idiopathic subvalvular aortic stenosis, severe hypertension, aneurysm or other severe cardiovascular disorders, such as ischaemic heart disease, tachyarrhythmias or severe heart failure.


  • Caution should be observed when treating patients with prolongation of the QTc-interval. Formoterol itself may induce prolongation of the QTc-interval.


  • As for all β2 adrenoceptor agonists, additional blood glucose controls should be considered in diabetic patients.


  • It is recommended that the height of children receiving prolonged treatment with inhaled corticosteroids is regularly monitored. If growth is slowed, therapy should be re-evaluated to reduce the dose of inhaled corticosteroid to the lowest dose at which effective control of asthma is maintained, if possible.


  • Corticosteroids may mask some signs of infection and new infections may appear. A

    decreased resistance to localized infection has been observed during corticosteroid therapy.


  • In patients with increased susceptibility to sympathomimetic amines (eg inadequately

    controlled hyperthyroidism), formoterol should be used with caution.


  • Physicians should be alerted to eosinophilia, vasculitic rash, worsening pulmonary

    symptoms, cardiac complications and/or neuropathy presenting in the patients.


  • This medicine contains lactose, for patients with rare hereditary problems of galactose

    intolerance, Lapp lactase deficiency or glucose-galactose malabsorption should not be taken.


Counselling Point:

To minimise the risk of oropharyngeal candida infection, the patient should be instructed to rinse their mouth out with water after inhaling the maintenance dose.


murtazacommunitypharmacy image showing formiget 400+12 mcg capsule strip

 
 
 
  • Dr. Hiba Yousuf Mughal
  • May 1
  • 2 min read

Updated: May 20

primolut n گولی کا استعمال


Written by Dr. Hiba Yousuf Mughal [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.


murtazacommunitypharmacy image showing primolut n tablet box

Brand name:

PRIMOLUT N ® 5 mg tablets


Generic name:

Norethisterone.


Available dosage forms and their doses:

Tablets


Price:

Rs. 380 per box


Therapeutic class:

synthetic hormone (chemical messenger) that mimics progesterone


Pharmacological class:

Progesterone Receptor agonist


Manufacturer:

OBS Pharmaceutical


Storage:

Store in the original packaging to protect from light.


Prescription drug:

Prescription Only Medicine

Clinical pharmacology (mechanism of action):

Norethisterone is a strong progestogen with negligible androgenic effects. Complete transformation of the endometrium from a proliferative to a secretory state can be achieved in oestrogen-primed women with orally administered doses of 100 - 150 mg norethisterone per cycle. The progestogenic effects of norethisterone on the endometrium are the basis of the treatment of dysfunctional bleeding, and endometriosis with PRIMOLUT N.


Gonadotropin secretion inhibition and anovulation can be achieved with a daily intake of 0.5 mg of norethisterone. Positive effects of PRIMOLUT Nnon premenstrual symptoms can be traced back to suppression of ovarian function. Due to the stabilising effects of norethisterone on the endometrium, administration of PRIMOLUT N can be used to shift the timing of menstruation. Like progesterone, the thermogenic action of norethisterone alters the basal body temperature.


Indications and dosages:

  • Dysfunctional bleeding

  • premenstrual syndrome

  • cyclical mastopathy

  • timing of menstruation

  • endometriosis

  • menorrhagia.


Dose:
The dose is 1 tablet of Primolut N three times daily, starting 3 days before the expected onset of menstruation and continuing for not longer than 10 to 14 days.

murtazacommunitypharmacy image showing primolut n tablet box with a strip of tablets

Side effects:

  • Immune system disorders: Hypersensitivity reactions

  • Nervous system disorders: Headache Migraine

  • Eye disorders: Visual disturbances

  • Respiratory, thoracic and mediastinal disorders: Dyspnoea

  • Gastrointestinal disorders: Nausea

  • Skin and subcutaneous tissue disorders: Urticaria, Rash

  • Reproductive system and breast disorders: Uterine/Vaginal bleeding including Spotting, Hypomenorrhoea, Amenorrhoea

  • General disorders at administration site conditions: Oedema.


Interactions:

Interactions have been reported for combined oral contraceptives.


Pregnancy:

The use of PRIMOLUT N during pregnancy is contraindicated. Pregnancy (Category

D): “Medicines which have caused, are suspected to have caused, or may be expected to

cause, an increased incidence of human foetal malformations or irreversible damage. These

medicines may also have adverse pharmacological effects.”


Lactation:

PRIMOLUT N should not be used during lactation


Precautions:

If any of the conditions/risk factors mentioned below is present or deteriorates,

an individual risk-benefit analysis should be done before PRIMOLUT N is started or continued.


This includes:

  • venous thromboembolism (VTE)

  • malignant liver tumours, diabetes

  • Chloasma may occasionally occur, especially in women with a history of chloasma gravidarum.


Counselling points:


A normal period should occur 2-3 days after the patient has stopped taking tablets.

 
 
 

© All Rights Reserved. Secured and Powered By HAMZA MURTAZA

bottom of page