empaa tablet uses

Written by Dr Taha Murtaza [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan)

Generic:

Empagliflozin

Available dosage forms:

• Empaa 10mg tablets

• Empaa 25 mg tablets

Prescription drug?

Yes

Manufacturer:

Weather Folds Pharmaceuticals.

Therapeutic class:

Anti-diabetic type 2 drug.

Pharmacological class:

SGLT-2 (sodium glucose co-transporter 2 inhibitor)

Mechanism of action:

It works by reducing reabsorption from kidney back into the systemic circulation and enhances glucose concentration in urine.

Indications:

Type 2 diabetes melitus

Dose:

10mg OD in morning with/without food.

Contra-indications:

• Severe renal impairment.

• Hypersensitivity to product.

Adverse Reactions:

• Hypotension

• Ketoacidosis

• Acute kidney injury and impairment in renal function

• Urosepsis

• pyelonephritis

• Hypoglycaemia

• Genetic mycotic infections

• Increases low density lipoprotein cholestrol LDLC

Interactions:

• Diuretics

• Insulin/insulin secretagogues

• 1,5 anhydroglucitol

Special populations:

• Pregnancy:

Not recommended in 2nd and 3rd trimesters of pregnancy.

• Lactation:

Not recommended

• Paeds:

Not recommended for <18 years age.

• Geriatrics:

No dose change is required

• Renal impairment:

Not recommended for severe renally impaired patients.

• Hepatic impairment:

It can be given to hepatically impaired patients:

Storage:

• Store below 30 degree celcius

• Protect from moisture and sunlight