mycitracin cream

mycitracin کریم

Written by Dr Syed Saad Ali [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan)

Mycitracin, a Triple Antibiotic First Aid Ointment, is a combination of multiple antibiotics used to relieve pain. Its petrolatum base soothes the healing of skin and protects it from skin abrasions, minor cuts, scrapes, nicks, and burns.

Brand Name:

MYCITRACIN® –Plus Pain Reliever Triple Antibiotic First Aid Ointment.

Generic Name:

Triple Antibiotics: Bacitracin, Neomycin Sulphate, and Polymyxin-B Sulphate

(Pain reliever) Lidocaine.

Available Dosage forms and their Doses:

Ointment 14.7 gms (Pack Size).

Price:

RS: 157-245 (Mycitracin Plus Ointment prices may fluctuate based on your location and the online store you purchase from).

Therapeutic Class:

First Aid Triple Antibiotic combination

Ointment is available as a Counter (OTC) product.

Pharmacological Class:

Topical Antibacterial Agents (Antibiotics).

Manufacturer:

Pfizer, a Pharmaceutical Industry Company.

Storage:

Store at a temperature of between 15˚-25˚C (59˚-77˚F).

Tamper-evident, fully sealed packets.

Check and do not use any open or torn packaged product.

Prescription Drug:

Available without a prescription, a non-prescription drug (OTC).

Clinical pharmacology (mechanism of action):

"This combination of three antibiotics plus a pain reliever that works by targeting and eliminating a range of gram-positive and gram-negative bacteria and prevents pain."

Component          Mechanism of Action with Spectrum

Bacitracin inhibits cell wall synthesis. (gram-positive bacteria)

Neomycin             Disrupts protein synthesis (30S ribosome). (Broad-spectrum)

Polymyxin B          Alters cell membrane permeability. (Gram-negative bacteria)

Lidocaine              Blocks sodium channels to inhibit nerve signals. (Analgesic response)

Indications and Dosages: 

Indicate the treatment and prophylaxis of superficial skin infections.

Dose: Apply a small portion of a thin layer of ointment over the affected area of skin, and if needed, then cover it with gauze dressings

Side effects:

These products don’t have any usual side effects; however, if you ever experience any unusual effects after application of this ointment, then contact your pharmacist or doctor.

Some of the rare side effects reported after use of these products include Uncomplicated skin infections or other bacterial and fungal infections.

If you observe any signs of a severe allergic reaction after application, such as a rash, dizziness, apnea (difficulty breathing), or itching or swelling, particularly in the face, lips, tongue, or neck, then immediately contact your healthcare provider, pharmacist, or doctor.

Interactions:

Drug interaction may interfere with the way how your medication works and increase the risk of side effects. It is important to keep a list of all prescription and OTC products you are using with it and show it to your healthcare provider for the provision of safe and effective therapy.

This heading does not include all interactions, but some of the common interactions include,

·         gentamicin

·         mivacurium

·         neomycin

·         netilmicin

·         pipecuronium

·         plazomicin

·         streptomycin

·         succinylcholine

·         tobramycin

Pregnancy:

No sufficient data is available regarding any negative signs of use of this product during pregnancy. However, this product can only be used when needed as per the advice of a doctor or pharmacist.

lactation:

It is unknown if the medications included in the product may pass into the mother's feed. It's better to consult your pharmacist before breastfeeding.

Precautions

·         Use for the External body only.

·         Avoid contact in contact with your eyes. If yes! Then wash immediately with clean warm water and contact your nearest doctor or pharmacist.

·         People who are allergic to any of the components present in this drug are advised to avoid this product.

·         Recommended to get the treatment within 7 days unless prescribed by your physician.

·         Keep out of the reach of children, in case of accidental ingestion accidentally then call the poison and drug control center right away.

Counselling points:

·         Wash and dry the affected area before applying.

·         Apply a thin layer 1–3 times a day or as directed.

·         Wash hands before and after use.