Vitamin D capsule (SG indrop D)

Generic:

Cholecalciferol (Vitamin D3)

Manufacturer:

Neutropharma pvt limited

Therapeutic class:

Nutritional supplement

Pharmacological class:

Bone resorption inhibitor and vitamin D3 agonist

Storage:

Store below 25 degrees Celsius

Prescription drug?

OTC/prescription

Avaiable dosage forms for sg indrop D capsule:

Sg indrop D capsule 5,000 IU, comes in a box of 30 softgel capsules.

Sg indrop D capsule 2,00,000 IU, comes in a box of one softgel capsule.

Pharmacology (Mechanism of action):

• Stimulates calcium resorption at renal tubule.

• Stimulates calcium and phosphate absorption from the small intestine.

• Stimulates secretion of calcium into blood from bones.

Pregnancy/lactation:

Accepted but only for the recommended dose, a higher dose than recommended is not accepted.

Indications and dosages

Adults

• Osteoporosis

Prophylaxis and treatment:

For >50 yrs: 800-1000 IV PO OD with calcium supplements.

• Hypothyroidism:

50,000-2,00,000 IU OD PO with calcium supplemets.

• Vitamin D resistant rickets:

  12,000-5,00,000 IU PO OD

• Familial hypophosphatemia

  10,000-50,000 PO OD

RDA for adults:

19-70 yrs: 600 IU PO OD.

Pregnancy/lactation: 600 IU PO OD.

Paeds

• Vitamin D resistant rickets:

  12,000-5,00,000 IU PO OD

• Familial hypophosphatemia:

  4,00,000-80,000 PO OD with phosphate supplement.

  
  

• RDA for paeds:

  0-12yrs: 400 IU OD IV

  1-18yr: 600 IU OD PO

Geriatrics:

RDA:

>70yrs: 800 IU PO OD.

<70yrs: 600 IU PO OD.

Interactions:

Serious:

• Pexidartinib

• Pretomanib

• Aluminium hydroxide

• calcium acetate

• calcium gluconate

• calcium carbonate

• digoxin

• indapamide

• magnesium citrate

• phenobarbital

• phenytoin

• sucralfate

• primidone

Adverse Effects:

• Asthma

• confusion

• headache

• constipation

• dry mouth

• hyperglycemia

• lethargy

• metallic taste

• muscle/bone pain

• nausea/vomiting

• sluggishness

  
  

  Counselling points:

• Don't give vitamin/mineral supplements and antacids with sg indrop D.

• Monitor your calcium level while using this medicine.

  
  

  Contra-indications:

• Allergy to cholecalciferol/any component of the medicine.

• High calcium level

• Hyperparathyroidism

• kidney disorder

• Histoplasmosis

• Granulomatous disorder

• Lymphomas

• Congenital disorder

• Dysregulated vitamin D3 metabolism