oncosten vial

onosten انجکشن

Written by Dr. Maryam [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.

Brand Name

Oncosten Injection

Dosage form:

Injection

Generic Composition (per vial)

· Carnitine (USP): 70 mg

· Ginseng Extract (MS): 270 mg

· Bilberry Extract (MS): 200 mg

· Royal Jelly (MS): 30 mg

· Potassium Chloride (USP): 100 mg

· Magnesium Sulphate (USP): 9.25 mg

Dosage:

Typical Doseage is 1 vial daily or on alternate days or as recommended by physician or pharmacist.

 Price Range

Approximately PKR 4000–5000 

Therapeutic Class

Nutritional Supplement

Pharmacological Class

•  Antioxidant and adaptogen

•  Electrolyte rebalancer

Manufacturer:  

Paradigm

Storage Instructions

• Store in cool and dry place

• Do not freeze

• Protect from heat

Prescription Status

Prescription Only

Mechanism of Action

· Carnitine supports cellular energy by transporting fatty acids into mitochondria.

· Ginseng acts as an adaptogen, reducing fatigue

· Bilberry Extract improves circulation

· Royal Jelly provides anti-inflammatory and antioxidant.

· Potassium and Magnesium restore vital electrolytes and support nerve and muscle function.

Indications

Oncosten Injection may be used as a supportive therapy in:

· Post-chemotherapy recovery

· Chronic fatigue or general weakness

· Nutritional deficiencies

· Immunity support

Side Effects

Some possible side effects include:

· Mild pain or swelling at injection site

· Dizziness or nausea

· Headache

 Drug Interactions

· May interact with potassium-sparing diuretics

· Ginseng may lower blood sugar

· Possible interaction with Anticoagulants

 Pregnancy

· Safety in pregnancy not established

 Lactation

· Not recommended

Precautions

· Use with caution in patients with kidney issues

· Monitor serum potassium levels with long-term use

· Administer slowly to avoid vein irritation

 Patient Counselling Tips

· Inform patients that the injection helps with energy, recovery and immunity

· Advise to report any allergic symptoms immediately

· Encourage patient to have a balanced diet and hydration along with therapy

· Reassure any mild soreness at the injection site

rovista tablet uses

رووسٹا گولی کا استعمال

Written by Dr. Noor Fatima [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.

Generic:

Rosuvastatin

Dosage forms:

Tablet forms are available in different strengths: 5mg, 10mg, 20mg, and

40mg.

Therapeutic class:

Lipid-lowering agent, Statins

Pharmacological class:

HMG-CoA Reductase Inhibitors

Price:

For 10mg tab (1 strip= 10 tablets)= RS 415

For 20mg tab (1 strip= 10 tablets)= RS 640

Mechanism of Action:

HMG-CoA reductase mediates the first committed step in sterol biosynthesis. The active forms of the reductase inhibitors are structural analogs of the HMG-CoA intermediate that is formed by HMG-CoA reductase in the synthesis of mevalonate. These agents block this action.

Manufacturer:

Getz Pharma

Storage:

25-30 degrees Celsius

Prescription Drug:

Rosuvastatin should be prescribed by the physician.

Indications and Doses:

Hypercholesterolemia: It is used as an adjunctive therapy in adults with hypertriglyceridemia, hyperlipidemia, and mixed dyslipidemia.

Dose: 10-20mg PO every day, not exceeding 40mg/ day.

Slowing the progression of Atherosclerosis: It is used as an adjunctive therapy in adult patients as a part of a treatment strategy to lower total cholesterol and LDL cholesterol to target levels.

Renal Dose Adjustment:

Mild or moderate (CrCl ≥30 mL/min/1.73m²): No dosage adjustment

necessary

Side Effects:

Prevention Of Cardiovascular Events in patients at high risk of a first cardiovascular event and with risk factors for myopathy or

rhabdomyolysis.

Avoid rosuvastatin creatinine clearance less than 30mL/minute.

Contraindications:

● Hypersensitivity to drug or excipients

● Acute liver failure or decompensated cirrhosis (including

unexplained persistent elevations of LFTs)

● Gemfibrozil may increase the toxicity of rosuvastatin.

Pregnancy:

Discontinue therapy when pregnancy is recognized; alternatively, consider ongoing therapeutic needs of individual patient.

Lactation:

No data available.

folic acid tablet uses

فولک ایسڈ کی گولی کا استعمال

Written by Dr. Qaisara Tehzeeb [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.

BRAND NAME:

· FOLIC ACID

GENERIC NAME:

· Folic acid (Folate or Vitamin B9)

AVAILABLE DOSAGE FORM:

· Folic Acid tablet BP 5mg

PRICE:

· 92 rupees per bottle, which contains 100 tablets of folic acid.

THERAPEUTIC CLASS:

· Member of water-soluble Vitamin B Complex.

· Prenatal Vitamin.

PHARMACOLOGICAL CLASS:

· Essential cofactor and precursor for enzymes required for nucleoprotein synthesis and maintenance of erythropoiesis.

MANUFACTURER:

· ZAFA Pharmaceutical Laboratories (Pvt.) Limited.

PRESCRIPTION DRUG?

· YES

MECHANISM OF ACTION:

· Folate acts as a precursor in the synthesis of Tetrahydrofolate (active form of folate), a cofactor which helps to perform various biochemical reactions such as DNA and RNA synthesis and the production of red blood cells.

INDICATIONS:

· Prevent and treat folic acid deficiency.

· Megaloblastic Anemia

· Macrocytic Anemia

· Prevent complications and birth defects during pregnancy, such as Spina Bifida

and Anencephaly.

DOSE:

· For adults and children over 1 year ( 5mg tablet once a day)

· For children less than 1 year of age (500 mcg per kg of body weight daily)

SIDE EFFECTS:

· Nausea

· Bloating

· Loss of Appetite

· Rash

· Sleep Problems

CONTRAINDICATIONS:

· Folic acid is generally safe, but in rare cases, it can cause an allergic reaction in some people.

· Pernicious anemia and aplastic anemia

· Cancer (unless you have folate deficiency)

DRUG INTERACTIONS:

· Anticonvulsants (Phenytoin, fosphenytoin and Primidone)

· Barbiturates

· Methotrexate (folate antagonist)

· Pyrimethamine

· Do not take your folic acid within 2 hours before or after taking antacids containing Aluminium and Magnesium, as they may stop folic acid from being properly absorbed.

PREGNANCY:

· Used by pregnant women as a dietary supplement to prevent neural tube defects.

 LACTATION:

· Recommended for breastfeeding women.

STORAGE:

· Store at room temperature away from light, heat and moisture.

INSTRUCTIONS:

· Folic acid can be beneficial for both kidney and liver health.

· Folic acid should never be used to treat anemia without a full investigation of the cause.

COUNSELLING:

· Keep out of the reach of children.

· Swallow the whole tablet with a glass of water.

· You can take folic acid before or after the meal.