Pakistan Navy forces Indian aircraft carrier to retreat in Arabian Sea

پاک بحریہ نے بھارتی طیارہ بردار جہاز کو بحیرہ عرب میں پیچھے ہٹنے پر مجبور کر دیا۔

Written by Dr. Taha Murtaza

The war between Pakistan and India, which was started as a result of a violation done by the Indian government in the agreement of the Indus River between the two states.

On 23rd April 2025, India sent an aircraft carrier ship named INS Vikrant into the Arabian Sea near the Pakistani coast. Indian Prime Minister Narendra Modi confirmed this activity.

In response to this activity, Pakistan's navy sent its F-16 fighter jet. After this act, India's Vikrant returned to its country as its movement was monitored by radar.

suzuki cultus price hike

سوزوکی کلٹس کی قیمتوں میں اضافہ

Written by Dr. Taha Murtaza

Suzuki Motors Pakistan announced increased prices of their cultus models on 26th April 2025.

This increase in prices has brought some new changes and advances in the features of cultus models, so cultus lovers can now enjoy some new benefits.

New features include:

• Rear center seat belt

• Rear head restraint

• Driver seat belt buzzer and display on speedometer

• Child seat garnish

• ISO-FIX anchor

• Front seat belt pre-tensioners

• Front seatbelt force-limiters

• Airbags (driver and passenger)

• Anti-lock braking system (ABS)

• Separate rear seat (60:40 split)

  
  

Retail Prices:

Including FED and S/Tax.

• VXR

  4,230,000PKR [15,056.06USD] (Forty-two lacs thirty and thousand rupess)

• VXL

  4,316,000PKR [15,362.16USD] (Forty-three lacs and sixteen thousand rupess)

• AGS

  4,618,000PKR [16,437.09USD] (Forty-six lacs and eighteen thousand rupess)

acefyl syrup

ایسفیل سیرپ

Written by Dr. Misbah Khan [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.

Brand:

Acefyl

Generic:

Acefylline Piperazine, Diphenhydramine

Dosage form:

Syrup

Doses:

For cough and respiratory issues:

• Adults: 10-20 mL three times daily

• Children (2-6 years): 5 mL three times daily

• Children (6-12 years): 10 mL three times daily

  
  

For chronic obstructive pulmonary disease (COPD):

• Adults: 10-20 mL three times daily

• Children (6-12 years): 10 mL three times daily

For allergic conditions:

• Adults: 10-20 mL three times daily

• Children (2-6 years): 5 mL three times daily

• Children (6-12 years): 10 mL three times daily

Price:

Rs156.75 (0.56$)

Therapeutic class:

Antihistamine

Pharmacology class:

Xanthine derivatives

Manufacturer:

Nabi Qasim Pharmaceuticals (Pvt) Ltd.

Storage:

Store it at a temperature between 15°C and 30°C in a cool, dry place,

away from direct sunlight and moisture.

Prescription drug:

Yes, it requires a prescription

Mechanism of action:

"It inhibits the PDE-4 enzyme, increasing cyclic adenosine monophosphate (cAMP) levels in cells, which reduces inflammation and improves respiratory symptoms."

Indications:

This medication is used to treat:

• Bronchial asthma

• Chronic bronchitis

• Obstructive airway diseases

• Bronchoconstriction

• Allergy symptoms

• Sneezing

• Runny nose

• Itching

Side effects:

• Nausea

• Drowsiness

• Stomach discomfort

• Diarrhea

• Allergic reactions

Interactions:

• Other xanthines (e.g., caffeine) (increased risk of side effects)

• Corticosteroids (increased risk of adverse effects)

• Beta-adrenergic agonists (increased risk of cardiovascular effects)

• Lithium (potential for increased lithium levels)

• CYP450 inducers (e.g., rifampin) (may reduce efficacy)

• CYP450 inhibitors (e.g., erythromycin) (may increase risk of toxicity)

• Alcohol (enhanced sedation and impairment)

• Benzodiazepines (increased sedation)

• MAO inhibitors (risk of severe hypertension)

• Anticholinergic drugs (increased anticholinergic effects)

• Opioids (enhanced sedation and respiratory depression)

• Tricyclic antidepressants (increased anticholinergic effects and sedation)

• Other CNS depressants (enhanced drowsiness and impaired cognitive

function)

Pregnancy:

According to the FDA (Food and Drug Administration), no evidence suggests Acefyl syrup poses a risk to pregnant women or their unborn babies. It can also help alleviate symptoms of cough and cold, which are common during pregnancy.

Lactation:

Breastfeeding women should consult their healthcare provider before using this syrup to ensure its safety.

Precautions:

This syrup may cause drowsiness; users should avoid activities requiring full mental alertness, such as driving or operating machinery until they understand how the syrup affects them.