CaC 1000 plus tablet

CaC 1000 پلس ٹیبلیٹ

Written by Dr. Khubaib [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.

✅ Brand Name

· CaC-1000 PLUS

✅ Generic Name

· Calcium (as Calcium Lactate Gluconate + Calcium Carbonate)

· Vitamin D3 (Cholecalciferol)

· Vitamin C (Ascorbic Acid)

· Vitamin B6 (Pyridoxine Hydrochloride)

✅ Available Dosage Forms and Doses

· Effervescent tablet (dissolvable in water)

·  Each tablet contains:

· Calcium (total) ≈ 1000 mg

· Vitamin D3 ≈ 400 IU

· Vitamin C ≈ 500 mg

· Vitamin B6 ≈ 10 mg

· Flavour: Orange

· How to use: Dissolve 1 tablet in a glass of water and drink.

✅ Price

· Approx. PKR 150 to 180 per tube of 10 tablets (may vary based on pharmacy/location)

✅ Therapeutic Class

· Mineral and Vitamin Supplement

· Bone and joint health

✅ Pharmacological Class

· Calcium supplement with vitamins

· Multivitamin-mineral combination

✅ Manufacturer

· GlaxoSmithKline (GSK) Consumer Healthcare Pakistan Ltd.

·  Pataro Road, Jamshoro

✅ Storage

· Keep below 30°C

· Store in a dry place

· Protect from moisture and direct sunlight

· Keep out of reach of children

✅ Prescription Drug?

· No – Available over the counter (OTC) in Pakistan

✅ Clinical Pharmacology (Mechanism of Action)

· Calcium is essential for bone formation, muscle function, and nerve transmission.

· Vitamin D3 increases calcium absorption from the intestine and regulates bone mineralization.

· Vitamin C helps in collagen formation and enhances calcium absorption.

· Vitamin B6 supports metabolism and helps reduce fatigue and weakness.

· Together, they help build and maintain strong bones, prevent deficiencies, and support overall metabolic function.

✅ Indications and Dosages

· Indications:

· Prevention and treatment of calcium and vitamin D deficiency

· Bone health in osteoporosis or osteopenia

· During pregnancy, lactation, or menopause

· Muscle cramps or weakness due to low calcium

· Healing of bone fractures

· Supporting general immune function

· Dosage:

· Adults: 1 tablet daily dissolved in a full glass of water, after a meal

· Can be increased to 1 tablet twice daily if prescribed by a doctor

✅ Side Effects

· Usually well tolerated. Possible mild effects:

· Nausea or bloating

· Stomach discomfort

· Gas

· Mild constipation

· Rare: high calcium levels (with excessive use)

✅ Drug Interactions

· Avoid using with:

· Iron, zinc, or magnesium supplements (space them out by 2 hours)

· Certain antibiotics (like tetracyclines, fluoroquinolones)

· Thyroid medications (e.g., levothyroxine)

· Diuretics (e.g., thiazides) – may increase calcium levels

· Antacids – check for overlapping ingredients

✅ Pregnancy

· Safe to use in pregnancy when taken in recommended doses.

·  Supports the increased calcium demand during pregnancy.

✅ Lactation

· Also safe during breastfeeding – calcium and vitamins are vital for both mother and baby.

✅ Precautions

· Use with caution if you have:

· Kidney stones

· Kidney disease

· High blood calcium levels (hypercalcemia)

· Sarcoidosis or other calcium-related disorders

· Avoid exceeding the daily recommended dosage unless advised.

✅ Counselling Points (Patient Advice)

· Always dissolve tablet fully in water before drinking

· Take after meals to reduce stomach upset

· Stay well hydrated throughout the day

· Don’t take it with milk or iron supplements – separate by 2 hours

Report if you notice nausea, weakness, confusion, or irregular heartbeat (possible signs of high calcium).