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Transamine capsule uses

  • Writer: Dr Taha and Dr Ikhlaq
    Dr Taha and Dr Ikhlaq
  • Mar 20
  • 1 min read

Updated: Mar 21


image showing transamine 250mg cap box

Generic:

Tranexamic acid


Manufacturer:

Hilton Pharma (Pvt) Ltd


Pharmacology (Mechanism of action):

It inhibits the action of plasmin and acts as a coagulant. It mainly prevents bleeding.


Available dosage forms:

  • Transamine 250 mg capsule

  • Transamine 500 mg capsule

  • Transamine 250 mg injection

  • Transamine 500 mg injection

  • Transamine S injection


Indications:

  • Leukaemia

  • Hypostatic anaemia

  • Abnormal bleeding (pulmonary, nasal, renal, genital or after prostate surgery.

  • Urticaria, eczema, day rash, toxic exanthema (erythema, swelling or itching)

  • Pharyngolaryngitis, tonsillitis (Pharyngodynia, redness, hyperemia or swelling)

  • Stomatitis pain in mucosal aphtha or oral cavity.

  • Post-partum haemorrhage

  • Dental extraction in patients with haemophilia.


Dosage and administration:

750-2000mg/day divided in 3-4 times.

image showing transamine 250mg capsules


Dose Adjustments:

Dose adjustments required for renaly impaired patients

image showing a chart of dosage adjustements for transamine 250/500mg capsules.

Adverse drug reactions:

  • Hypersensitivity

  • Digestive problems

  • Dermatologic problems

  • Convulsions

  • Drowsiness

  • Retinal changes (in dogs)


Interactions:

  • With coagulant drugs


Contra- indications:


  • In patients with acquired defective color vision

  • In patients with sub-arachnoid haemorrhage

  • In patients with active intravascular clotting


Side effects:

  • Anorexia

  • Nausea/vomiting

  • pyrosis

  • Itching

  • Rash


Storage:


  • Store below 30 degree celcius.

  • Protect from sunlight and moisture


image showing transamine 500mg capsules

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