CaC 1000 plus tablet

CaC 1000 پلس ٹیبلیٹ

Written by Dr. Khubaib [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.

✅ Brand Name

· CaC-1000 PLUS

✅ Generic Name

· Calcium (as Calcium Lactate Gluconate + Calcium Carbonate)

· Vitamin D3 (Cholecalciferol)

· Vitamin C (Ascorbic Acid)

· Vitamin B6 (Pyridoxine Hydrochloride)

✅ Available Dosage Forms and Doses

· Effervescent tablet (dissolvable in water)

·  Each tablet contains:

· Calcium (total) ≈ 1000 mg

· Vitamin D3 ≈ 400 IU

· Vitamin C ≈ 500 mg

· Vitamin B6 ≈ 10 mg

· Flavour: Orange

· How to use: Dissolve 1 tablet in a glass of water and drink.

✅ Price

· Approx. PKR 150 to 180 per tube of 10 tablets (may vary based on pharmacy/location)

✅ Therapeutic Class

· Mineral and Vitamin Supplement

· Bone and joint health

✅ Pharmacological Class

· Calcium supplement with vitamins

· Multivitamin-mineral combination

✅ Manufacturer

· GlaxoSmithKline (GSK) Consumer Healthcare Pakistan Ltd.

·  Pataro Road, Jamshoro

✅ Storage

· Keep below 30°C

· Store in a dry place

· Protect from moisture and direct sunlight

· Keep out of reach of children

✅ Prescription Drug?

· No – Available over the counter (OTC) in Pakistan

✅ Clinical Pharmacology (Mechanism of Action)

· Calcium is essential for bone formation, muscle function, and nerve transmission.

· Vitamin D3 increases calcium absorption from the intestine and regulates bone mineralization.

· Vitamin C helps in collagen formation and enhances calcium absorption.

· Vitamin B6 supports metabolism and helps reduce fatigue and weakness.

· Together, they help build and maintain strong bones, prevent deficiencies, and support overall metabolic function.

✅ Indications and Dosages

· Indications:

· Prevention and treatment of calcium and vitamin D deficiency

· Bone health in osteoporosis or osteopenia

· During pregnancy, lactation, or menopause

· Muscle cramps or weakness due to low calcium

· Healing of bone fractures

· Supporting general immune function

· Dosage:

· Adults: 1 tablet daily dissolved in a full glass of water, after a meal

· Can be increased to 1 tablet twice daily if prescribed by a doctor

✅ Side Effects

· Usually well tolerated. Possible mild effects:

· Nausea or bloating

· Stomach discomfort

· Gas

· Mild constipation

· Rare: high calcium levels (with excessive use)

✅ Drug Interactions

· Avoid using with:

· Iron, zinc, or magnesium supplements (space them out by 2 hours)

· Certain antibiotics (like tetracyclines, fluoroquinolones)

· Thyroid medications (e.g., levothyroxine)

· Diuretics (e.g., thiazides) – may increase calcium levels

· Antacids – check for overlapping ingredients

✅ Pregnancy

· Safe to use in pregnancy when taken in recommended doses.

·  Supports the increased calcium demand during pregnancy.

✅ Lactation

· Also safe during breastfeeding – calcium and vitamins are vital for both mother and baby.

✅ Precautions

· Use with caution if you have:

· Kidney stones

· Kidney disease

· High blood calcium levels (hypercalcemia)

· Sarcoidosis or other calcium-related disorders

· Avoid exceeding the daily recommended dosage unless advised.

✅ Counselling Points (Patient Advice)

· Always dissolve tablet fully in water before drinking

· Take after meals to reduce stomach upset

· Stay well hydrated throughout the day

· Don’t take it with milk or iron supplements – separate by 2 hours

Report if you notice nausea, weakness, confusion, or irregular heartbeat (possible signs of high calcium).

sibelium tablet uses

سیبیلیم گولی کا استعمال

Written by Dr. Kashmala [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.

Brand name

Sibelium

Generic name

Flunarizine

Available dosage forms and their doses

Cap 5mg and Tab 10mg in some countries

Price

242 Rupees

Available in packs containing 12 capsules

Therapeutic class:

Anti-migraine agent

Pharmacological class

Calcium channel blocker

Manufacturer:

Aspin Pharma Pvt. Ltd

Storage

below 30°C

Prescription drug?

Yes, Sibelium (Flunarizine) is a prescription-only medication

Clinical pharmacology (mechanism of action)

It inhibits voltage-gated calcium channels and shows antihistaminic and sedative properties.

Indications and dosages

Migraine Prevention, Vertigo and Balance Disorders, Cerebral Vascular Disorders, Epilepsy

Dosage

For Adults, mg to 10 mg daily

For Elderly Patients (above 65 years): a lower dose of 5 mg daily is recommended

Side effects

Drowsiness or Sedation, Weight Gain, Dry Mouth, Constipation, Fatigue, Depression or Mood Changes                      

Interactions

Benzodiazepines, e.g., diazepam, lorazepam, Antidepressants and Antipsychotics(e.g., fluoxetine, sertraline), and antipsychotic medications (e.g., haloperidol, risperidone), antihypertensive drugs (e.g., beta-blockers like propranolol)

Pregnancy

Category C: Flunarizine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus

Lactation

Flunarizine is known to be excreted in breast milk. While it is not recommended to take Sibelium while breastfeeding unless

Precautions

Allergic Reactions, Liver Disease, Extrapyramidal Symptoms, Cardiovascular Conditions, 

Counselling points:

• Take once daily, preferably at bedtime, to minimize drowsiness.

• Swallow the capsule whole with water. Do not crush or chew it.

• Stick to the prescribed dose; do not exceed it or stop abruptly without consulting your

  doctor. This medication is not intended for lifelong use unless advised by a physician.

• Often reviewed after 5-6 months to evaluate effectiveness and safety.

Halus Lotion

ہالوس لوشن

Written by Dr. Hiba Yousuf Mughal [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.

Brand name:

Halus Extra Moisturizing Lotion

Generic name:

Glycerin, Dimethicone

Available dosage forms and their doses:

150ml 

Price:

1360 Rs.

Therapeutic class:

Emollients

Pharmacological class:

Emollients

Manufacturer: 

Incepta Pharma

Storage:

store below 300C. Protect from heat, light & moisture.

Prescription drug:

As directed by the physician

Clinical pharmacology (mechanism of action):

Works by enhancing skin hydration and reinforcing the skin's natural barrier function, which helps to retain moisture and protect against dryness.

Indications:

1.      Helps prevent and temporarily protect chafed, chapped, or cracked skin

2.      Helps protect from the drying effects of wind and cold weather.

Side effects:

1.      Skin Irritation: Some users may experience mild irritation, such as redness or itching, especially if they have sensitive skin or are allergic to any of the ingredients.

2.      Breakouts: In some cases, individuals with oily or acne-prone skin might experience breakouts or increased oiliness.

3.      Allergic Reactions: Rarely, users might experience severe allergic reactions, such as rash, swelling, or difficulty breathing. If these symptoms occur, discontinue use and seek medical attention.

Interactions:

No serious interactions have been reported.

Pregnancy:

The drug is not absorbed systemically following topical administration; use during pregnancy would not be expected to result in significant exposure to the fetus

Lactation:

The drug is not absorbed systemically following topical administration; exposure via breast milk would not be expected.

Precautions:

1.      Patch Test: It’s advisable to perform a patch test before using the lotion to ensure you do not have an allergy or sensitivity to any of the ingredients. Apply a small amount to a discreet area of skin and observe for any adverse reactions.

2.      Avoid Contact with Eyes: Avoid applying the lotion near the eyes. If contact occurs, rinse thoroughly with water.

3.      Consult a Healthcare Provider: If you have specific skin conditions, are pregnant, or are breastfeeding, consult a healthcare provider before using the lotion to ensure it’s appropriate for your skin type and situation.

4.      Use as Directed: Follow the instructions on the product label for proper application. Overuse may lead to irritation or other issues.

Counselling points:

Always refer to the product’s label and manufacturer’s guidelines for the most accurate and detailed information. If you have any concerns or experience adverse effects, consult your healthcare provider.

• For External Use Only

• Do not use on - deep or puncture wounds, animal bites, or serious burns.

• Do not get into the eyes