sibelium tablet uses

سیبیلیم گولی کا استعمال

Written by Dr. Kashmala [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.

Brand name

Sibelium

Generic name

Flunarizine

Available dosage forms and their doses

Cap 5mg and Tab 10mg in some countries

Price

242 Rupees

Available in packs containing 12 capsules

Therapeutic class:

Anti-migraine agent

Pharmacological class

Calcium channel blocker

Manufacturer:

Aspin Pharma Pvt. Ltd

Storage

below 30°C

Prescription drug?

Yes, Sibelium (Flunarizine) is a prescription-only medication

Clinical pharmacology (mechanism of action)

It inhibits voltage-gated calcium channels and shows antihistaminic and sedative properties.

Indications and dosages

Migraine Prevention, Vertigo and Balance Disorders, Cerebral Vascular Disorders, Epilepsy

Dosage

For Adults, mg to 10 mg daily

For Elderly Patients (above 65 years): a lower dose of 5 mg daily is recommended

Side effects

Drowsiness or Sedation, Weight Gain, Dry Mouth, Constipation, Fatigue, Depression or Mood Changes                      

Interactions

Benzodiazepines, e.g., diazepam, lorazepam, Antidepressants and Antipsychotics(e.g., fluoxetine, sertraline), and antipsychotic medications (e.g., haloperidol, risperidone), antihypertensive drugs (e.g., beta-blockers like propranolol)

Pregnancy

Category C: Flunarizine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus

Lactation

Flunarizine is known to be excreted in breast milk. While it is not recommended to take Sibelium while breastfeeding unless

Precautions

Allergic Reactions, Liver Disease, Extrapyramidal Symptoms, Cardiovascular Conditions, 

Counselling points:

• Take once daily, preferably at bedtime, to minimize drowsiness.

• Swallow the capsule whole with water. Do not crush or chew it.

• Stick to the prescribed dose; do not exceed it or stop abruptly without consulting your

  doctor. This medication is not intended for lifelong use unless advised by a physician.

• Often reviewed after 5-6 months to evaluate effectiveness and safety.

Halus Lotion

ہالوس لوشن

Written by Dr. Hiba Yousuf Mughal [PharmD, DOW University Of Health Sciences (DUHS)], Karachi, Pakistan.

Brand name:

Halus Extra Moisturizing Lotion

Generic name:

Glycerin, Dimethicone

Available dosage forms and their doses:

150ml 

Price:

1360 Rs.

Therapeutic class:

Emollients

Pharmacological class:

Emollients

Manufacturer: 

Incepta Pharma

Storage:

store below 300C. Protect from heat, light & moisture.

Prescription drug:

As directed by the physician

Clinical pharmacology (mechanism of action):

Works by enhancing skin hydration and reinforcing the skin's natural barrier function, which helps to retain moisture and protect against dryness.

Indications:

1.      Helps prevent and temporarily protect chafed, chapped, or cracked skin

2.      Helps protect from the drying effects of wind and cold weather.

Side effects:

1.      Skin Irritation: Some users may experience mild irritation, such as redness or itching, especially if they have sensitive skin or are allergic to any of the ingredients.

2.      Breakouts: In some cases, individuals with oily or acne-prone skin might experience breakouts or increased oiliness.

3.      Allergic Reactions: Rarely, users might experience severe allergic reactions, such as rash, swelling, or difficulty breathing. If these symptoms occur, discontinue use and seek medical attention.

Interactions:

No serious interactions have been reported.

Pregnancy:

The drug is not absorbed systemically following topical administration; use during pregnancy would not be expected to result in significant exposure to the fetus

Lactation:

The drug is not absorbed systemically following topical administration; exposure via breast milk would not be expected.

Precautions:

1.      Patch Test: It’s advisable to perform a patch test before using the lotion to ensure you do not have an allergy or sensitivity to any of the ingredients. Apply a small amount to a discreet area of skin and observe for any adverse reactions.

2.      Avoid Contact with Eyes: Avoid applying the lotion near the eyes. If contact occurs, rinse thoroughly with water.

3.      Consult a Healthcare Provider: If you have specific skin conditions, are pregnant, or are breastfeeding, consult a healthcare provider before using the lotion to ensure it’s appropriate for your skin type and situation.

4.      Use as Directed: Follow the instructions on the product label for proper application. Overuse may lead to irritation or other issues.

Counselling points:

Always refer to the product’s label and manufacturer’s guidelines for the most accurate and detailed information. If you have any concerns or experience adverse effects, consult your healthcare provider.

• For External Use Only

• Do not use on - deep or puncture wounds, animal bites, or serious burns.

• Do not get into the eyes

Bunyan Al Marsoos: Pakistan launched an operation of steadfast missile strikes against India on May 10, 2025. What exactly does " mean?

Written by Dr. Syed Saad Ali

BUNYAN AL MARSOOS "بنیان المرصوص," an Arabic verse taken from the Quran, the holy book of Allah.

"The operation's name, which means "a structure firmly joined together," is inspired by SURAH AL-SAIF (61:4), which praises those who fight in Allah's fortified cause as a solid, concrete structure."

"إِنَّ ٱللَّهَ يُحِبُّ ٱلَّذِينَ يُقَـٰتِلُونَ فِى سَبِيلِهِۦ صَفًّۭا كَأَنَّهُم بُنْيَـٰنٌۭ مَّرْصُوصٌۭ"

On May 10, 2025, Pakistan started Operation Bunyan Al Marsoos—a planned sequence of missile attacks intended at Indian military targets, signifying a move from deterrence to direct action. The chief of the Pak Army Staff (COAS), General Syed Asim Munir, offered Fajr prayers and recited Surah Al-Saif before the launch of the strategic operation, trusting in divine direction.

Dr. Israr Ahmad, the late Islamic expert, has previously commented on this Quranic passage during one of his lectures. He compared "Real Mujahideen" to "Bunyan un Marsoos"—men with iron wills and steel nerves, unified like bricks in a wall, and cherished by Allah for their diligence and dedication in Jihad. His interpretation lends spiritual meaning to Pakistan's selection of the operation's name.

What happened after this key mission

• Their BrahMos storage site was wrecked.

• S-400 battery neutralized.

• Over 15 airbases were targeted.

• Five Rafales were downed.

• One Su-30MKI was destroyed.

• One MiG-29 was lost.

• The brigade headquarters were targeted and destroyed.

• Squadron ldr. Shivangi Singh, India's first female Rafale pilot, has reportedly been arrested by Pakistan.

  
  

Some of the Indian military bases known to be targeted so far:

• Udhampur airbase: The northern HQ of the Indian army is located in occupied Kashmir.

• Pathankot Airbase: The central frontline airbase of Indian Air Force operations.

• Drangyari artillery gun position: In Indian-occupied Jammu and Kashmir.

• Uri field: Uri, a field located in Kashmir (occupied), is a major Indian armed forces base that was attacked in 2016, in which 19 Indian soldiers were killed ahead of the war.

• Nagrota: A storage site of the Brahmos site.

• Beas: Located in the Punjab side of India, the storage site of Brahmos missiles.

• Adampur air base: At this site, the Indian S-400 system was destroyed.

• Bhuj air base: Located in the Kutch district of Indian Gujrat.

  
  

It went on to state that Pakistan had finally kept its pledge. "The entire world has seen Pakistan's response to the Indian aggression." Pakistan Zindabad!